Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1194171 | 0.99 | ACHE (0.32) | ACHEKDM4EALDH1A1LMNAHCAR3 | |
| SCHEMBL6595709 | 0.89 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1194041 | 0.88 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNA | |
| SCHEMBL6598073 | 0.83 | ALDH1A1 (0.38) | ACHEKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1194173 | 0.82 | ALDH1A1 (0.37) | ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL6599190 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL1194170 | 0.78 | — | — | |
| SCHEMBL6596219 | 0.78 | MAPT (0.35) | KDM4EALDH1A1LMNA | |
| SCHEMBL6596187 | 0.77 | KMT2A (0.35) | KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1193715 | 0.77 | MAPT (0.34) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |