Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1193915 | 0.99 | KMT2A (0.35) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL6598073 | 0.87 | ALDH1A1 (0.38) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1194173 | 0.86 | ALDH1A1 (0.37) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL6595709 | 0.84 | ALDH1A1 (0.38) | KMT2AMEN1LMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL1194041 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL6598288 | 0.80 | ALDH1A1 (0.37) | KMT2AMEN1LMNAMAPTMAPK1 | |
| Bromide SCHEMBL1194181 | 0.79 | ALDH1A1 (0.36) | KMT2AMEN1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6599921 | 0.79 | LMNA (0.34) | KMT2AMEN1LMNAMAPK1ALDH1A1 | |
| SCHEMBL6599195 | 0.77 | ACHE (0.32) | LMNAALDH1A1KDM4E | |
| SCHEMBL6596219 | 0.77 | MAPT (0.35) | KMT2AMEN1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |