Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 8/20 | 0.34 |
| ▸ | FABP6 | P51161 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097277 | 0.76 | PARP1 (0.43) | ALDH1A1MEN1KMT2ATYMSKDM4E | |
| SCHEMBL4639811 | 0.72 | POLB (0.37) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL694986 | 0.72 | NPC1 (0.55) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL694946 | 0.69 | PKN1 (0.56) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL3499660 | 0.68 | NUDT1 (0.48) | ALDH1A1NUDT1MASP2MEN1KMT2A | |
| SCHEMBL694892 | 0.67 | ALOX5 (0.48) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL5539351 | 0.67 | PDGFRB (0.39) | ALDH1A1KDM4EGAA | |
| SCHEMBL5541674 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL695165 | 0.66 | GAA (0.44) | KMT2AKDM4EGAAMAPT | |
| SCHEMBL30587443 | 0.66 | ALDH1A1 (1.00) | ALDH1A1NUDT1MASP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385833-A1 | TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | Amgen Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083654-A1 | TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AMGEN INC. (US) | 2002-10-24 | — | — | WO | disclosed |