Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601577 | 0.90 | MGLL (0.58) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7046095 | 0.79 | MGLL (0.74) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7571649 | 0.78 | MGLL (0.72) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7044315 | 0.77 | MGLL (0.62) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL6615026 | 0.76 | MGLL (0.75) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7045989 | 0.75 | MGLL (0.66) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7046148 | 0.74 | MGLL (0.78) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7046042 | 0.73 | MGLL (0.72) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL7042914 | 0.73 | MGLL (1.00) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL29499689 | 0.73 | MGLL (1.00) | MGLLFAAHLPLLIPCLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |