Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599507 | 0.90 | MGLL (0.57) | MGLLFAAHNPC1RAB9AKDM4E | |
| SCHEMBL7046095 | 0.81 | MGLL (0.74) | MGLLFAAHKDM4EALDH1A1HPGD | |
| SCHEMBL7571649 | 0.79 | MGLL (0.72) | MGLLFAAHNPC1RAB9AKDM4E | |
| SCHEMBL6615026 | 0.77 | MGLL (0.75) | MGLLFAAHKDM4EALDH1A1HPGD | |
| SCHEMBL7045989 | 0.76 | MGLL (0.66) | MGLLFAAHNPC1RAB9AKDM4E | |
| SCHEMBL7046042 | 0.74 | MGLL (0.72) | MGLLFAAHALDH1A1ABHD16ALPL | |
| SCHEMBL7042914 | 0.73 | MGLL (1.00) | MGLLFAAHNPC1RAB9AMAOB | |
| SCHEMBL29499689 | 0.73 | MGLL (1.00) | MGLLFAAHNPC1RAB9AMAOB | |
| SCHEMBL7656723 | 0.73 | MGLL (0.62) | MGLLFAAHNPC1RAB9AKDM4E | |
| SCHEMBL7045977 | 0.73 | MGLL (0.62) | MGLLFAAHNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |