Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | HTR6 | P50406 | 2/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.71 |
| ▸ | HTR7 | P34969 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.65 |
| ▸ | MC5R | P33032 | 1/20 | 0.64 |
| ▸ | MC3R | P41968 | 1/20 | 0.64 |
| ▸ | MC1R | Q01726 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11602872 | 0.98 | HTR2A (0.70) | HTR2AHTR1AHTR6DRD2HTR7 | |
| Oxalic Acid SCHEMBL6603520 | 0.93 | KMT2A (0.67) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL28413707 | 0.88 | HRH3 (0.63) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL7015692 | 0.88 | HRH3 (0.67) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL8263255 | 0.88 | HTR2A (0.65) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL8265592 | 0.86 | MEN1 (0.62) | KMT2AHRH3MEN1SMN1; SMN2MAPT | |
| SCHEMBL19778568 | 0.85 | HRH3 (0.67) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL7011744 | 0.85 | GOT1 (0.70) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL8264766 | 0.84 | CDK2 (0.61) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL7006163 | 0.84 | DRD2 (0.73) | HTR2AHTR1AHTR6DRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683552-B | Tryptamine salicylic acid compound and preparation and application thereof | 兰州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-113683552-A | Tryptamine salicylic acid compound and preparation and application thereof | 兰州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-107552089-A | Application and application process of a kind of quinine squaric amide derivative as asymmetric P S reacting middle catalysts | 浙江工业大学 | 2018-01-09 | — | — | CN | disclosed |
| EP-1379239-A2 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002078693-A2 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2002-10-10 | — | — | WO | disclosed |
| US-4372887-A | DIURETIC, ANTITHROMBOGENIC, SMOOTH MUSCLE RELAXANTS | MEAD JOHNSON & COMPANY (US) | 1983-02-08 | — | — | US | disclosed |
| US-4259238-A | ANTIARRHYTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4196212-A | DIURETIC, ANTITHROMBOGENIC, SMOOTH MUSCLE RELAXANT, ANTIINFLAMMATORY | MEAD JOHNSON & COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4091102-A | Anti-depressant trans-hexahydropyrido[3,4-b]indoles | ENDO LABORATORIES, INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4072675-A | DIURETICS, ANTICOAGULANTS, INOTROPIC AGENTS, ANTIINFLAMMATORY AGENTS, ANTIARRHYTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
| US-4049714-A | DIURETIC, ANTITHROMBOGENIC, ANTIARRYTHMIC, ANTIINFLAMMATORY, MUSCLE RELAXANTS | MEAD JOHNSON & COMPANY (US) | 1977-09-20 | — | — | US | disclosed |