Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 4/20 | 0.54 |
| ▸ | PTPRB | P23467 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602038 | 1.00 | CTSS (0.54) | CTSSCTSBCTSKPTPRBTSHR | |
| SCHEMBL6600244 | 0.89 | CTSS (0.45) | CTSSCTSBCTSKZAP70SRC | |
| SCHEMBL6605282 | 0.89 | CTSB (0.45) | CTSSCTSBCTSKPTPRBTSHR | |
| SCHEMBL6600359 | 0.89 | CTSS (0.59) | CTSSCTSBCTSKPTPRBTSHR | |
| SCHEMBL6600356 | 0.89 | CTSS (0.59) | CTSSCTSBCTSKPTPRBTSHR | |
| SCHEMBL6599890 | 0.87 | TSHR (0.58) | CTSSCTSBCTSKTSHRALDH1A1 | |
| SCHEMBL6605301 | 0.84 | MMP2 (0.43) | CTSSCTSBCTSKTSHRZAP70 | |
| SCHEMBL6600399 | 0.84 | MMP2 (0.47) | CTSSCTSBZAP70SRCCTSL | |
| Hydrochloric Acid SCHEMBL6600392 | 0.84 | MMP2 (0.46) | CTSSCTSBZAP70SRCCTSL | |
| SCHEMBL6601179 | 0.83 | KLKB1 (0.48) | CTSSZAP70SRCCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |