Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.69 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | NQO2 | P16083 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798092 | 0.88 | KMT2A (0.80) | KMT2APOLBTRPV1MTNR1AMTNR1B | |
| SCHEMBL6919747 | 0.83 | TRPV1 (0.88) | KMT2APOLBTRPV1MTNR1AMTNR1B | |
| SCHEMBL28663007 | 0.81 | KMT2A (0.87) | KMT2APOLBTRPV1MTNR1AMTNR1B | |
| SCHEMBL6930033 | 0.81 | MTNR1A (0.81) | KMT2APOLBTRPV1MTNR1AMTNR1B | |
| SCHEMBL3219747 | 0.80 | KMT2A (0.77) | KMT2APOLBTRPV1MTNR1AMTNR1B | |
| SCHEMBL9936354 | 0.80 | TRPV1 (1.00) | KMT2APOLBTRPV1MTNR1AMEN1 | |
| SCHEMBL23644935 | 0.79 | MTNR1A (0.83) | KMT2APOLBTRPV1MTNR1AMTNR1B | |
| Melatonin SCHEMBL4686085 | 0.79 | MTNR1A (1.00) | KMT2APOLBMTNR1AMTNR1BMEN1 | |
| Melatonin SCHEMBL29349848 | 0.79 | MTNR1A (1.00) | KMT2APOLBMTNR1AMTNR1BMEN1 | |
| Melatonin SCHEMBL19018 | 0.79 | MTNR1A (1.00) | KMT2APOLBMTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085392-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085395-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |
| EP-1462103-A1 | NO donors, combination products and uses as modulators of neurotransmitter release | Faust Pharmaceuticals (FR) | 2004-09-29 | — | — | EP | disclosed |