Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | ACE | P12821 | 4/20 | 0.38 |
| ▸ | GHSR | Q92847 | 5/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933422 | 1.00 | MMP9 (0.44) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL6600613 | 0.91 | GHSR (0.46) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL13808413 | 0.87 | MMP9 (0.40) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL3726874 | 0.87 | MMP9 (0.40) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL13808414 | 0.87 | MMP9 (0.40) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL6600520 | 0.87 | CTSB (0.41) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL6600517 | 0.87 | CTSB (0.41) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL6600943 | 0.85 | GHSR (0.48) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL6600948 | 0.85 | GHSR (0.48) | MMP9MMP8MMEACEGHSR | |
| SCHEMBL6603214 | 0.83 | CTSB (0.41) | MMP9MMP8MMEACEGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | claimed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |