Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 7/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603208 | 1.00 | CTSB (0.41) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL6600517 | 0.91 | CTSB (0.41) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL6600520 | 0.91 | CTSB (0.41) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL6320628 | 0.88 | CTSS (0.52) | CTSBCTSSCTSKMMP9MMP8 | |
| SCHEMBL6602261 | 0.87 | GHSR (0.41) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL6600613 | 0.87 | GHSR (0.46) | GHSRMMP9MMP8MMEACE | |
| SCHEMBL6600530 | 0.83 | MMP9 (0.44) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL8933422 | 0.83 | MMP9 (0.44) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL6602254 | 0.80 | GHSR (0.43) | CTSBCTSSCTSKGHSRMMP9 | |
| SCHEMBL6602251 | 0.80 | GHSR (0.43) | CTSBCTSSCTSKGHSRMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |