Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600548 | 0.80 | TP53 (0.31) | — | |
| SCHEMBL6601364 | 0.80 | PGR (0.37) | ALDH1A1POLBHSD17B10 | |
| SCHEMBL6598640 | 0.79 | CCR2 (0.47) | CCR2ALDH1A1POLBHSD17B10 | |
| SCHEMBL6602150 | 0.78 | CCR2 (0.48) | CCR2ALDH1A1POLBHSD17B10 | |
| SCHEMBL6597519 | 0.77 | — | — | |
| SCHEMBL6598791 | 0.77 | KMT2A (0.49) | ALDH1A1POLBHSD17B10PTGS2SMN1; SMN2 | |
| SCHEMBL6597036 | 0.77 | CNR1 (0.33) | — | |
| SCHEMBL6600027 | 0.75 | PDE5A (0.34) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6600915 | 0.75 | PDE5A (0.34) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6600909 | 0.74 | PDE5A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |