Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600027 | 0.99 | PDE5A (0.34) | PDE5AKMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL6600915 | 0.99 | PDE5A (0.34) | PDE5AKMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL6598987 | 0.81 | KMT2A (0.33) | PDE5AKMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL6601063 | 0.81 | MCL1 (0.40) | PDE5AKMT2AF2RL3PTGESALOX5 | |
| SCHEMBL6597890 | 0.80 | MAOB (0.40) | PDE5AKMT2AF2RL3PTGESALOX5 | |
| SCHEMBL6601472 | 0.80 | KMT2A (0.40) | KMT2AF2RL3PTGESALOX5MAOB | |
| SCHEMBL6600548 | 0.78 | TP53 (0.31) | — | |
| SCHEMBL6599527 | 0.75 | THRA (0.42) | KMT2A | |
| SCHEMBL6601208 | 0.74 | CCR2 (0.35) | — | |
| SCHEMBL6597519 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |