Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368774 | 0.81 | KMT2A (0.50) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL6848360 | 0.79 | KMT2A (0.55) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL6846654 | 0.77 | KMT2A (0.51) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL3763346 | 0.77 | LMNA (0.58) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL5988773 | 0.77 | ALDH1A1 (0.53) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL6607044 | 0.76 | NQO2 (0.52) | POLBL3MBTL1LMNAALDH1A1 | |
| SCHEMBL6618425 | 0.75 | TERT (0.39) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6846717 | 0.74 | KMT2A (0.52) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL7761439 | 0.74 | KMT2A (0.52) | HTTKMT2ASMN1; SMN2MITFJAK2 | |
| SCHEMBL3895339 | 0.74 | HTT (0.63) | HTTTP53KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |