Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073181 | 0.83 | TERT (0.55) | NQO2KDM4ELMNAPOLBCASP6 | |
| SCHEMBL6618425 | 0.82 | TERT (0.39) | NQO2KDM4ELMNAALDH1A1CASP1 | |
| SCHEMBL5409128 | 0.79 | MAP4K4 (0.41) | NQO2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL3235863 | 0.77 | NCF1 (0.63) | NQO2KDM4ELMNAPOLBCASP6 | |
| SCHEMBL6846673 | 0.77 | CYP1A2 (0.57) | NQO2KDM4ELMNAPOLBCASP6 | |
| SCHEMBL6955172 | 0.76 | CRHR1 (0.48) | LMNATERTCRHR1LATS1LATS2 | |
| SCHEMBL6600636 | 0.76 | HTT (0.53) | LMNAPOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30579056 | 0.75 | NCF1 (0.61) | NQO2KDM4ELMNAPOLBCASP6 | |
| SCHEMBL5420608 | 0.74 | CRHR1 (0.44) | POLBTERTCRHR1LATS1LATS2 | |
| SCHEMBL3390039 | 0.74 | NQO2 (0.53) | NQO2KDM4ELMNAPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |