Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 9/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600261 | 0.86 | CYP26A1 (0.33) | ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL8314291 | 0.82 | KMT2A (0.43) | MAOBALKALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6598980 | 0.76 | POLB (0.33) | MAOBALDH1A1LMNATDP1 | |
| SCHEMBL5810419 | 0.75 | PPARD (0.53) | F2RL3ALDH1A1LMNA | |
| SCHEMBL8312063 | 0.74 | ALOX5 (0.34) | MAOBALDH1A1 | |
| SCHEMBL6598601 | 0.74 | F2RL3 (0.38) | F2RL3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5810509 | 0.73 | F2RL3 (0.38) | MAOBF2RL3 | |
| SCHEMBL6598958 | 0.73 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL5807179 | 0.73 | KMT2A (0.33) | MAOBALDH1A1LMNA | |
| SCHEMBL8315448 | 0.73 | ALOX5 (0.34) | MAOBF2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |