Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614139 | 0.86 | TERT (0.43) | TERTLMNAALDH1A1CASP1CASP7 | |
| SCHEMBL6618425 | 0.83 | TERT (0.39) | TERTLMNAALDH1A1CASP1CASP7 | |
| SCHEMBL13701566 | 0.82 | LMNA (0.58) | TERTLMNAALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL6616872 | 0.81 | TERT (0.40) | TERTLMNAALDH1A1HSD17B10ALOX15 | |
| SCHEMBL4073181 | 0.81 | TERT (0.55) | TERTLMNAALDH1A1CASP1CASP7 | |
| SCHEMBL6618332 | 0.78 | ADORA2A (0.54) | LMNAALDH1A1HSD17B10MAPK1ADORA2A | |
| SCHEMBL6617731 | 0.77 | TERT (0.51) | TERTLMNAALDH1A1CASP1CASP7 | |
| SCHEMBL6790532 | 0.77 | CYP1A2 (0.60) | TERTALDH1A1CYP1A2ADORA2ANCF1 | |
| SCHEMBL5849336 | 0.76 | TERT (0.64) | TERTALOX15L3MBTL1NQO2 | |
| SCHEMBL6616973 | 0.75 | NCF1 (0.59) | TERTALDH1A1CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401833-A2 | CHEMICAL DERIVATIVES AND THE USE THEREOF AS AN ANTI-ELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-03-31 | — | — | EP | disclosed |
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002096903-A2 | CHEMICAL DERIVATIVES AND THE USE THEREOF AS AN ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |