SCHEMBL6790532

SCHEMBL6790532

Cc1cc(N(C)C)c2ccccc2n1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.60
NCF1 P14598 4/20 0.56
ACP1 P24666 2/20 0.51
TERT O14746 2/20 0.50
ADORA2A P29274 1/20 0.47
KDM1A O60341 1/20 0.47
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6790530 0.85 CYP1A2 (0.56) CYP1A2NCF1KDM4EUSP2ALDH1A1
SCHEMBL30367038 0.83 CYP1A2 (0.50) CYP1A2NCF1KDM1AKDM4EALDH1A1
SCHEMBL30367104 0.80 CYP1A2 (0.50) CYP1A2NCF1KDM1A
SCHEMBL29419409 0.79 ACP1 (0.50) CYP1A2ACP1KDM1AKDM4EUSP2
SCHEMBL5431607 0.79 ACP1 (0.50) CYP1A2ACP1KDM1AKDM4EUSP2
SCHEMBL13701566 0.79 LMNA (0.58) CYP1A2TERTKDM1AKDM4EALDH1A1
SCHEMBL6458326 0.79 BACE1 (0.59) NCF1ACP1KDM1AKDM4EALDH1A1
SCHEMBL30367213 0.79 CYP1A2 (0.49) CYP1A2NCF1KDM1AKDM4EALDH1A1
SCHEMBL4863068 0.79 NCF1 (0.50) CYP1A2NCF1KDM4EALDH1A1MAPT
SCHEMBL4073181 0.78 TERT (0.55) CYP1A2NCF1TERTADORA2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4087889-B1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS LLC (US) 2024-03-06 EP claimed
US-11697701-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof PROMERUS, LLC (US) 2023-07-11 US claimed
US-11692056-B2 Stable polycycloolefin polymer and inorganic nanoparticle compositions as optical materials PROMERUS, LLC (US) 2023-07-04 US claimed
EP-4087889-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF Promerus, LLC (US) 2022-11-16 EP claimed
US-11299573-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof PROMERUS LLC (US) 2022-04-12 US claimed
US-20210221931-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS, LLC (US) 2021-07-22 US claimed
WO-2021142402-A1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS, LLC (US) 2021-07-15 WO claimed
WO-2021016503-A1 STABLE POLYCYCLOOLEFIN POLYMER AND INORGANIC NANOPARTICLE COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-01-28 WO claimed
US-20210024685-A1 STABLE POLYCYCLOOLEFIN POLYMER AND INORGANIC NANOPARTICLE COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-01-28 US claimed
US-12037431-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof PROMERUS, LLC (US) 2024-07-16 US disclosed
EP-4087889-B1 STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF PROMERUS LLC (US) 2024-03-06 EP disclosed
EP-4288479-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2023-12-13 EP disclosed
US-11697701-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof PROMERUS, LLC (US) 2023-07-11 US disclosed
US-11692056-B2 Stable polycycloolefin polymer and inorganic nanoparticle compositions as optical materials PROMERUS, LLC (US) 2023-07-04 US disclosed
US-20090226411-A1 CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS AVENTIS PHARMA S.A. (FR) 2009-09-10 US disclosed
US-7482352-B2 Chemical derivatives and their application as antitelomerase agents AVENTIS PHARMA S.A. (FR) 2009-01-27 US disclosed
US-7482352-B2 Chemical derivatives and their application as antitelomerase agents AVENTIS PHARMA S.A. (FR) 2009-01-27 US disclosed
US-6825215-B2 N-HYDROXY-2-(2-(((4-((2-METHYL-4-QUINOLINYL)METHOXY)PHENYL) -SULFONYL)METHYL)-2-PYRROLIDINYL)ACETAMIDE, FOR EXAMPLE AND OTHER QUINOLINE CONTAINING N-HYDROXYACETAMIDE DERIVATIVES BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-11-30 US disclosed
EP-1355901-A2 1,1-DISUBSTITUTED CYCLIC INHIBITORS OF MATRIX METALLOPROTEASE AND TNF-$g(a) Bristol-Myers Squibb Pharma Company (US) 2003-10-29 EP disclosed
WO-2002055516-A2 1,1-DISUBSTITUTED CYCLIC INHIBITORS OF MATRIX METALLOPROTEASE AND TNF-$g(a) BRISTOL MYERS SQUIBB CO (US) 2002-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226411-A1 CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS DPYD, NTPCR, NME1 CYP1A2 1561/4885NCF1 1011/4885ACP1 1582/4885
US-11697701-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof RRP15, PPOX, NONO CYP1A2 1047/4885NCF1 2660/4885ACP1 438/4885
US-12037431-B2 Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof RRP15, PPOX, NONO CYP1A2 1047/4885NCF1 2660/4885ACP1 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.