Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 12/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917975 | 0.81 | ERN1 (0.58) | ERN1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL8401591 | 0.81 | ALDH1A1 (0.40) | ERN1POLBMAPTKDM4ETHRB | |
| SCHEMBL31551017 | 0.80 | ERN1 (0.49) | ERN1 | |
| SCHEMBL5600053 | 0.80 | ALDH1A1 (0.50) | POLBMAPTKDM4ETHRBRECQL | |
| SCHEMBL24236790 | 0.79 | ERN1 (0.50) | ERN1P2RX1 | |
| SCHEMBL30054964 | 0.79 | ERN1 (0.53) | ERN1POLBMAPT | |
| SCHEMBL30711864 | 0.79 | TDP1 (0.35) | ERN1POLBMAPTKDM4ETHRB | |
| SCHEMBL660446 | 0.79 | ERN1 (0.53) | ERN1POLBMAPT | |
| SCHEMBL660134 | 0.79 | TDP1 (0.35) | ERN1POLBMAPTKDM4ETHRB | |
| SCHEMBL22366835 | 0.78 | TDP1 (0.38) | ERN1POLBMAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116608-B | N-benzyl aniline derivatives with free radical scavenging effect and pharmaceutical application thereof | 南京医科大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-111116608-A | N-benzyl aniline derivatives with free radical scavenging effect and pharmaceutical application thereof | 南京医科大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-2774914-B1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | UNIV NANJING MEDICAL (CN) | 2017-12-06 | — | — | EP | disclosed |
| US-9481636-B2 | N-benzylaniline derivative and uses thereof | NANJING MEDICAL UNIVERSITY (CN) | 2016-11-01 | — | — | US | disclosed |
| CN-103086908-B | N-benzylaniline derivatives and application thereof | UNIV NANJING MEDICAL | 2015-05-13 | — | — | CN | disclosed |
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140303248-A1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | Neurodawn Pharmaceutical Co., Ltd. (CN) | 2014-10-09 | — | — | US | disclosed |
| EP-2774914-A1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | Nanjing Medical University (CN) | 2014-09-10 | — | — | EP | disclosed |
| WO-2012024494-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| EP-2376441-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | Dow AgroSciences LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2376435-A2 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | Dow AgroSciences LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010083307-A2 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010083307-A2 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010083310-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010083310-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | ERN1 3396/4885POLB 4572/4885MAPT 1491/4885 |
| US-20140303248-A1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | NLN, INA, TRPV1 | ERN1 1346/4885POLB 3593/4885MAPT 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.