SCHEMBL660446

SCHEMBL660446

O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 13/20 0.53
CES2 O00748 2/20 0.39
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30054964 1.00 ERN1 (0.53) ERN1CES2POLBMAPT
SCHEMBL10333575 0.87 ERN1 (0.49) ERN1
SCHEMBL24236790 0.81 ERN1 (0.50) ERN1CES2
SCHEMBL660083 0.79 ERN1 (0.58) ERN1POLBMAPT
SCHEMBL658153 0.79 ERN1 (0.64) ERN1
SCHEMBL29592823 0.79 ERN1 (0.58) ERN1
SCHEMBL10323583 0.79 ERN1 (0.58) ERN1
SCHEMBL391593 0.79 CES2 (0.45) ERN1CES2POLB
SCHEMBL30711834 0.78 CES2 (0.36) ERN1CES2POLBMAPT
SCHEMBL6903282 0.78 ERN1 (0.36) ERN1CES2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230180754-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2023-06-15 US disclosed
EP-4149936-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2023-03-22 EP disclosed
WO-2021228594-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2021-11-18 WO disclosed
CN-103179857-B Synergistic algicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC 2015-03-18 CN disclosed
US-8906829-B2 Synergistic algicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC (US) 2014-12-09 US disclosed
US-8906829-B2 Synergistic algicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC (US) 2014-12-09 US disclosed
EP-2605653-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER Dow AgroSciences LLC (US) 2013-06-26 EP disclosed
US-20120148682-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-06-14 US disclosed
US-20120148682-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-06-14 US disclosed
US-20120046170-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-02-23 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
WO-2010083307-A2 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO disclosed
WO-2010083307-A2 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO disclosed
WO-2010083310-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO disclosed
WO-2010083310-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO disclosed
US-20090124787-A1 Method for Producing Polyhydroxyalkanoates BASF AKTIENGESELLSCHAFT (DE) 2009-05-14 US disclosed
US-20090124787-A1 Method for Producing Polyhydroxyalkanoates BASF AKTIENGESELLSCHAFT (DE) 2009-05-14 US disclosed
EP-1874845-B1 METHOD FOR PRODUCING POLYHYDROXYALKANOATES BASF SE (DE) 2008-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 ERN1 3396/4885CES2 719/4885POLB 4572/4885
US-20230180754-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS DDT, ACHE, CYCS ERN1 2252/4885CES2 1620/4885POLB 4701/4885
US-20120148682-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, CYP4Z1 ERN1 3190/4885CES2 509/4885POLB 4241/4885
US-20090124787-A1 Method for Producing Polyhydroxyalkanoates LDHB, ACADM, HSD17B12 ERN1 1195/4885CES2 236/4885POLB 509/4885
US-20120046170-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER ALG1, SOD1, DHPS ERN1 3581/4885CES2 1998/4885POLB 3009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.