Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592438 | 0.80 | GPR35 (0.51) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 | |
| SCHEMBL6597066 | 0.79 | GPR35 (0.47) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 | |
| SCHEMBL6601321 | 0.76 | GPR35 (0.44) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 | |
| SCHEMBL6593728 | 0.76 | MARS1 (0.42) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 | |
| SCHEMBL6080083 | 0.73 | IGFBP5 (0.36) | KDM4EIGFBP3PIM1IGFBP5MAPT | |
| SCHEMBL28233478 | 0.73 | GPR35 (0.49) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 | |
| SCHEMBL6081171 | 0.73 | KDM4E (0.41) | KDM4EL3MBTL1ALOX15IGFBP3PIM1 | |
| SCHEMBL6592433 | 0.72 | PTGER1 (0.46) | — | |
| SCHEMBL975858 | 0.70 | ALOX15 (0.56) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 | |
| SCHEMBL1166810 | 0.69 | GPR35 (0.50) | GPR35KDM4EL3MBTL1ALOX15IGFBP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |