Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600506 | 1.00 | AVPR2 (0.43) | AVPR2AVPR1ABDKRB1HTTUGCG | |
| SCHEMBL27971723 | 0.82 | BCHE (0.39) | BDKRB1ALDH1A1SMN1; SMN2BCHE | |
| SCHEMBL6601659 | 0.82 | EGFR (0.48) | HTTKDM4EHSD17B10BCHE | |
| SCHEMBL6441669 | 0.76 | MAPK1 (0.40) | BDKRB1BCHE | |
| Hydrochloric Acid SCHEMBL29960696 | 0.76 | BCHE (0.38) | BCHE | |
| SCHEMBL6244927 | 0.74 | SMN1; SMN2 (0.51) | HTTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL29960503 | 0.72 | HTR6 (0.40) | BCHE | |
| SCHEMBL8367985 | 0.72 | EGFR (0.45) | BDKRB1ALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL5500008 | 0.71 | HSD17B10 (0.41) | BDKRB1HSD17B10BCHE | |
| Hydrochloric Acid SCHEMBL29960649 | 0.70 | BCHE (0.39) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877736-B1 | BENZAZEPINE DERIVATIVES WITH VASOPRESSIN AGONISTIC ACTIVITY | OTSUKA PHARMA CO LTD (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6096736-A | Benzazepine derivatives with vasopressin agonistic activity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0877736-A1 | BENZAZEPINE DERIVATIVES WITH VASOPRESSIN AGONISTIC ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997022591-A1 | BENZAZEPINE DERIVATIVES WITH VASOPRESSIN AGONISTIC ACTIVITY | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-06-26 | — | — | WO | disclosed |