Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601659 | 0.86 | EGFR (0.48) | BCHEEGFRCACNA1G | |
| SCHEMBL27971723 | 0.81 | BCHE (0.39) | BCHEEGFRBDKRB1 | |
| SCHEMBL6443098 | 0.79 | CRBN (0.44) | IDO1EGFRCACNA1G | |
| SCHEMBL6441308 | 0.79 | CRBN (0.44) | IDO1EGFRCACNA1G | |
| SCHEMBL6600506 | 0.76 | AVPR2 (0.43) | BCHEBDKRB1 | |
| SCHEMBL6438487 | 0.76 | CACNA1G (0.35) | IDO1NOD2NOD1CACNA1GKMT2A | |
| SCHEMBL6601609 | 0.76 | AVPR2 (0.43) | BCHEBDKRB1 | |
| SCHEMBL31686030 | 0.75 | CYP1A2 (0.47) | MAPK1BCHEIDO1KMT2AL3MBTL1 | |
| SCHEMBL26644922 | 0.75 | CYP1A2 (0.47) | MAPK1BCHEIDO1KMT2AL3MBTL1 | |
| SCHEMBL19984920 | 0.75 | MTNR1A (0.47) | NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |