Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935698 | 0.78 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL13087343 | 0.77 | ALDH1A1 (0.56) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11808597 | 0.77 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11808595 | 0.77 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11445100 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11630836 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11445101 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL660190 | 0.75 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL6206512 | 0.74 | ALDH1A1 (0.53) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11493419 | 0.74 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | Zhejiang Wild Wind Pharmaceutical Co., Ltd. (CN) | 2012-02-23 | — | — | US | disclosed |
| EP-2351730-A1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | Shanghai Ecust Biomedicine Co., Ltd (CN) | 2011-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | TUBB1, TUBB, TUBB3 | MEN1 4614/4885KMT2A 4287/4885MAPT 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.