Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.57 |
| ▸ | LIPC | P11150 | 1/20 | 0.57 |
| ▸ | LIPE | Q05469 | 1/20 | 0.57 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 3/20 | 0.46 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043932 | 0.77 | LPL (0.56) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL31635262 | 0.77 | L3MBTL1 (0.69) | L3MBTL1PTPRCPTPN13HDAC8HDAC3 | |
| SCHEMBL7042329 | 0.76 | MGLL (0.61) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL7046445 | 0.73 | MGLL (0.62) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL7047919 | 0.72 | LPL (1.00) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL6600164 | 0.72 | FAAH (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6600553 | 0.72 | LPL (0.62) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL13529755 | 0.71 | HDAC8 (0.64) | L3MBTL1PTPRCPTPN13HDAC8HDAC3 | |
| SCHEMBL6551089 | 0.71 | ABHD16A (0.67) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL31054382 | 0.70 | HDAC8 (0.62) | L3MBTL1PTPRCPTPN13HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |