Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 5/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080321 | 0.92 | MET (0.49) | METSIRT6HTR6LRRK2USP2 | |
| SCHEMBL6597732 | 0.91 | POLB (0.48) | METLRRK2POLBCYP2D6CYP2C9 | |
| SCHEMBL6597740 | 0.91 | POLB (0.48) | METLRRK2POLBCYP2D6CYP2C9 | |
| SCHEMBL6602382 | 0.90 | ALDH1A1 (0.44) | POLBMAPTMAPK1KMT2A | |
| SCHEMBL6080327 | 0.85 | SIRT6 (0.44) | METSIRT6HTR6CYP2D6CYP2C9 | |
| SCHEMBL6080362 | 0.84 | POLB (0.45) | METLRRK2POLBCYP2C9MAPT | |
| SCHEMBL6081022 | 0.84 | ALDH1A1 (0.49) | MAPTMAPK1KMT2A | |
| SCHEMBL6594175 | 0.81 | CTSV (0.44) | POLB | |
| SCHEMBL6594775 | 0.81 | CTSV (0.44) | POLB | |
| SCHEMBL6594769 | 0.81 | CTSV (0.44) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |