Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LPL | P06858 | 1/20 | 0.50 |
| ▸ | LIPC | P11150 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601880 | 0.89 | ALDH1A1 (0.54) | ALDH1A1LMNAABHD16AFAAHMGLL | |
| SCHEMBL6601946 | 0.80 | LPL (0.57) | ALDH1A1LPLLIPCLIPEABHD16A | |
| SCHEMBL15750288 | 0.78 | ALDH1A1 (0.73) | ALDH1A1LMNAEPHX2TP53MAPT | |
| SCHEMBL15741799 | 0.76 | ALDH1A1 (0.78) | ALDH1A1LMNANAMPTEPHX2EPHX1 | |
| SCHEMBL15741891 | 0.74 | ALDH1A1 (0.74) | ALDH1A1LMNANAMPTEPHX2MAPT | |
| SCHEMBL15741800 | 0.74 | ALDH1A1 (0.74) | ALDH1A1LMNANAMPTEPHX2MAPT | |
| SCHEMBL15741880 | 0.74 | ALDH1A1 (0.74) | ALDH1A1LMNAEPHX2EPHX1 | |
| SCHEMBL15741881 | 0.74 | ALDH1A1 (0.97) | ALDH1A1LMNANAMPTEPHX2EPHX1 | |
| SCHEMBL15750284 | 0.73 | ALDH1A1 (0.68) | ALDH1A1LMNANAMPTEPHX2EPHX1 | |
| SCHEMBL15750291 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNANAMPTEPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |