SCHEMBL6602946

SCHEMBL6602946

CC(=O)CC(=O)CC(=O)OC(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
GAA P10253 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
LMNA P02545 2/20 0.41
FAAH O00519 4/20 0.40
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
KDM4E B2RXH2 3/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012855 0.91 LMNA (0.46) TSHRGAALMNAFAAHHSD17B10
SCHEMBL182320 0.88 MGAM (0.55) TSHRGAAMGAMSIMGAM2
SCHEMBL29438274 0.88 MGAM (0.55) TSHRGAAMGAMSIMGAM2
SCHEMBL20477581 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2
SCHEMBL20481946 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2
SCHEMBL20477578 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2
SCHEMBL7134829 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2
SCHEMBL20482195 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2
SCHEMBL17433673 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2
SCHEMBL17433665 0.86 MGAM (0.52) TSHRGAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1219173-B1 INSECTICIDES AND ACARICIDES AGRO KANESHO CO LTD (JP) 2004-06-16 EP disclosed
US-20030191171-A1 Pyrazolyl compound AGRO-KANESHO CO., LTD. (JP) 2003-10-09 US disclosed
CN-1399515-A Insecticidal and acaricidal agents AGERO KANSHO CO LTD (JP) 2003-02-26 CN disclosed
US-20020156115-A1 Insecticidal and acaricidal composition, and methods of using the same AGRO-KANESHO CO., LTD. (JP) 2002-10-24 US disclosed
EP-1219173-A1 INSECTICIDAL AND ACARICIDAL AGENTS Agro-Kanesho Co., Ltd. (JP) 2002-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156115-A1 Insecticidal and acaricidal composition, and methods of using the same GSTO1, CBR3, CBR1 TSHR 1972/4885GAA 2425/4885MGAM 2725/4885
US-20030191171-A1 Pyrazolyl compound GSTO1, CBR3, GSTM1 TSHR 1212/4885GAA 3320/4885MGAM 3455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.