Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027786 | 0.90 | LDHA (0.37) | LDHAEGFRUTS2RAKT1 | |
| SCHEMBL6604227 | 0.88 | LDHA (0.46) | LDHAEGFRUTS2R | |
| SCHEMBL6603727 | 0.88 | LDHA (0.37) | LDHAEGFRUTS2RGPR55 | |
| SCHEMBL6604489 | 0.86 | LDHA (0.40) | LDHAEGFRUTS2RAKT1 | |
| SCHEMBL6603974 | 0.86 | ALDH1A1 (0.38) | LDHAEGFRUTS2RGPR55CNR2 | |
| SCHEMBL6604662 | 0.82 | LDHA (0.36) | LDHAEGFRUTS2RSLC6A2SLC6A4 | |
| SCHEMBL6606198 | 0.81 | LDHA (0.39) | LDHAEGFRUTS2R | |
| SCHEMBL6606237 | 0.79 | LDHA (0.43) | LDHAGPR55CNR2FFAR1 | |
| SCHEMBL9027789 | 0.78 | LDHA (0.38) | LDHAEGFRUTS2RAKT1 | |
| SCHEMBL6605035 | 0.78 | LDHA (0.42) | LDHAEGFRUTS2RAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142887-B1 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents | PARKE DAVIS & CO (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1142887-A1 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents | PARKE, DAVIS & COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5936128-A | BENZENETHIOL COMPOUNDS AS INTERMEDIATES; BACTERICIDES, VIRICIDES; HIV | WARNER-LAMBERT COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| US-5840751-A | ADMINISTERING IN THE TREATMENT OF INFECTION OR DISEASE CAUSED BY A RETROVIRUS | WARNER-LAMBERT COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| US-5789440-A | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents | WARNER-LAMBERT COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995014012-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |
| WO-1995014011-A2 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |