Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602958 | 0.90 | LDHA (0.38) | LDHAEGFRUTS2RAKT1 | |
| SCHEMBL9026445 | 0.87 | ALDH1A1 (0.38) | LDHAGPR84DAOEGFRUTS2R | |
| SCHEMBL6606198 | 0.87 | LDHA (0.39) | LDHAEGFRUTS2RDHODH | |
| SCHEMBL6604489 | 0.81 | LDHA (0.40) | LDHAEGFRUTS2RDHODHAKT1 | |
| SCHEMBL6604227 | 0.81 | LDHA (0.46) | LDHAEGFRUTS2R | |
| SCHEMBL6603727 | 0.81 | LDHA (0.37) | LDHAEGFRUTS2R | |
| SCHEMBL9026058 | 0.79 | LDHA (0.43) | LDHAGPR84DAO | |
| SCHEMBL6603974 | 0.78 | ALDH1A1 (0.38) | LDHADAOEGFRUTS2R | |
| SCHEMBL9027789 | 0.77 | LDHA (0.38) | LDHAEGFRUTS2RAKT1 | |
| SCHEMBL6604662 | 0.77 | LDHA (0.36) | LDHADAOEGFRUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729463-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |