Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616835 | 0.80 | MCHR1 (0.44) | NOS3NOS1NOS2ACHENQO2 | |
| SCHEMBL4073181 | 0.80 | TERT (0.55) | TERTEGFRNQO2KDM4EPOLB | |
| SCHEMBL6605394 | 0.76 | NUDT1 (0.44) | TERTEGFRACHENQO2KDM4E | |
| SCHEMBL6599742 | 0.76 | ALDH1A1 (0.46) | ACHEMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4824439 | 0.74 | ADORA2A (0.54) | EGFRACHEKDM4ELMNAMAPT | |
| SCHEMBL6600141 | 0.70 | EGFR (0.44) | EGFRKDM4EPOLBLMNACASP6 | |
| SCHEMBL27314053 | 0.69 | KDM4E (0.58) | EGFRNOS3NOS1NOS2ACHE | |
| SCHEMBL6606041 | 0.69 | NQO2 (0.50) | TERTACHENQO2KDM4EPOLB | |
| SCHEMBL4820817 | 0.69 | ACP1 (0.43) | EGFRACHEKDM4EPOLBLMNA | |
| SCHEMBL4823424 | 0.68 | MAP4K4 (0.43) | ACHEKDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |