Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 4/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073181 | 0.88 | TERT (0.55) | NQO2LMNAPOLBKDM4ECASP6 | |
| SCHEMBL6614139 | 0.79 | TERT (0.43) | NQO2LMNAPOLBKDM4ENR4A2 | |
| SCHEMBL6600579 | 0.79 | POLB (0.64) | POLBNR4A2TERTKMT2A | |
| SCHEMBL6639402 | 0.78 | POLB (0.61) | NQO2LMNAPOLBKDM4ECASP6 | |
| SCHEMBL6790532 | 0.77 | CYP1A2 (0.60) | KDM4ETERTNCF1ADORA2A | |
| SCHEMBL6607835 | 0.76 | TERT (0.46) | POLBKDM4ENR4A2TERTNCF1 | |
| SCHEMBL11690458 | 0.75 | NQO2 (0.53) | NQO2LMNAPOLBKDM4ECASP6 | |
| SCHEMBL10818642 | 0.74 | MDM4 (0.43) | NQO2LMNAPOLBKDM4ECASP6 | |
| SCHEMBL13701566 | 0.71 | LMNA (0.58) | LMNAKDM4ETERTKMT2AMAOA | |
| SCHEMBL10005317 | 0.71 | NQO2 (0.49) | NQO2LMNAPOLBKDM4ECASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |