Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598958 | 0.91 | ALDH1A1 (0.37) | ALDH1A1HSD17B10POLBKMT2AMEN1 | |
| SCHEMBL7473185 | 0.88 | SMN1; SMN2 (0.44) | ALDH1A1HSD17B10POLBPKMKMT2A | |
| SCHEMBL5813234 | 0.84 | HPGD (0.36) | ALDH1A1HSD17B10PKMKMT2AMEN1 | |
| SCHEMBL6598493 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HSD17B10POLBCHRNB2CHRNA7 | |
| SCHEMBL5813890 | 0.82 | PPARG (0.38) | PLA2G2AMAOB | |
| SCHEMBL5811087 | 0.80 | THRA (0.40) | ALDH1A1KMT2ANPC1HPGDPLA2G2A | |
| SCHEMBL5813886 | 0.80 | THRA (0.38) | POLBKMT2AMEN1PLA2G2ALMNA | |
| SCHEMBL6599665 | 0.80 | PLA2G2A (0.39) | ALDH1A1KMT2APLA2G2ACYP26A1CYP26B1 | |
| SCHEMBL5807179 | 0.79 | KMT2A (0.33) | ALDH1A1PKMKMT2APLA2G2AMAOB | |
| SCHEMBL6601187 | 0.78 | PLA2G2A (0.49) | ALDH1A1KMT2APLA2G2ACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |