Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718749 | 0.84 | MAPT (0.48) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL17979799 | 0.82 | NUDT1 (0.56) | HRH3HRH4NR1I2SMARCA2SMARCA4 | |
| SCHEMBL5791956 | 0.81 | CRHBP (0.55) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL2450233 | 0.81 | CRHBP (0.57) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| Formic Acid SCHEMBL17979810 | 0.76 | NUDT1 (0.49) | HRH3HRH4NR1I2SMARCA2SMARCA4 | |
| SCHEMBL5790289 | 0.76 | CRHBP (0.50) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL2451697 | 0.76 | CRHBP (0.50) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL21491406 | 0.74 | CRHBP (0.59) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL21491405 | 0.74 | CRHBP (0.59) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL21491459 | 0.74 | CRHBP (0.59) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |