Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605680 | 0.86 | LTA4H (0.55) | CYP2D6CYP2C19LTA4HMCHR1 | |
| SCHEMBL6594650 | 0.82 | LTA4H (0.60) | ITGA4LTA4H | |
| SCHEMBL6596911 | 0.82 | LTA4H (0.55) | ITGA4LTA4HMCHR1 | |
| SCHEMBL6962455 | 0.80 | LTA4H (0.62) | LTA4HTDP1MCHR1 | |
| Hydrochloric Acid SCHEMBL9068571 | 0.74 | LTA4H (0.56) | ITGA4ESR1ESR2LTA4H | |
| SCHEMBL7768288 | 0.73 | ITGA4 (0.56) | ITGA4ESR1ESR2LTA4H | |
| SCHEMBL7441443 | 0.73 | ESR1 (0.56) | ESR1ESR2LTA4H | |
| SCHEMBL29573150 | 0.72 | TDP1 (0.66) | CYP1A2CYP2D6CYP2C19HSD17B10LTA4H | |
| SCHEMBL6596114 | 0.72 | LTA4H (0.52) | APPESR1ESR2CD274LTA4H | |
| SCHEMBL14397182 | 0.71 | TSHR (0.67) | CYP1A2CYP2D6CYP2C19HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244655-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-02-18 | — | — | EP | disclosed |
| US-6620837-B1 | 1-Benzothiophene derivatives | ELI LILLY AND COMPANY | 2003-09-16 | — | — | US | disclosed |
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |