Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603827 | 0.90 | MEN1 (0.58) | MCHR1MEN1KMT2APOLBPAX8 | |
| SCHEMBL6604698 | 0.88 | KMT2A (0.56) | MCHR1MEN1KMT2APOLBPAX8 | |
| SCHEMBL6604033 | 0.87 | KMT2A (0.55) | MCHR1MEN1KMT2APOLBPAX8 | |
| SCHEMBL6922588 | 0.82 | MCHR1 (0.67) | MCHR1MEN1KMT2AHTR2CMAPT | |
| SCHEMBL6602378 | 0.80 | MCHR1 (0.64) | MCHR1MEN1KMT2AHTR2CMAPT | |
| SCHEMBL6925443 | 0.77 | MCHR1 (0.81) | MCHR1HTR2C | |
| SCHEMBL6603153 | 0.76 | RAB9A (0.53) | MCHR1MEN1KMT2AHTR2CMAPT | |
| SCHEMBL6926161 | 0.76 | MCHR1 (0.76) | MCHR1HTR2CALDH1A1RAB9A | |
| SCHEMBL6924942 | 0.76 | MCHR1 (0.75) | MCHR1HTR2C | |
| SCHEMBL6899093 | 0.76 | MCHR1 (0.93) | MCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |