Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MITF | O75030 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604698 | 0.94 | KMT2A (0.56) | KMT2AMEN1POLBPAX8MAPT | |
| SCHEMBL6603827 | 0.90 | MEN1 (0.58) | KMT2AMEN1POLBPAX8MAPT | |
| SCHEMBL6604028 | 0.87 | MCHR1 (0.57) | KMT2AMEN1POLBPAX8MAPT | |
| SCHEMBL6602387 | 0.80 | TSHR (0.59) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL6603162 | 0.76 | RAB9A (0.53) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL6899096 | 0.76 | MCHR1 (0.70) | MCHR1 | |
| SCHEMBL6927024 | 0.75 | MCHR1 (0.66) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL6895401 | 0.74 | MCHR1 (0.70) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6900622 | 0.74 | MEN1 (0.51) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL6605524 | 0.74 | KMT2A (0.68) | KMT2AMEN1POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |