Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26796099 | 0.77 | SOS2 (0.40) | SOS2AHRSRCCTSKCTSS | |
| SCHEMBL30468476 | 0.76 | SOS2 (0.39) | SOS2GRM5CTSKCTSS | |
| SCHEMBL2954296 | 0.76 | SOS2 (0.39) | SOS2GRM5CTSKCTSS | |
| SCHEMBL13217258 | 0.73 | KDM4E (0.50) | — | |
| SCHEMBL7770340 | 0.73 | AHR (0.49) | SOS2AHRSRCGRM5CTSK | |
| SCHEMBL13217362 | 0.72 | KDM4E (0.45) | SOS2 | |
| SCHEMBL13217511 | 0.72 | ALDH1A1 (0.49) | — | |
| SCHEMBL2953350 | 0.71 | SQOR (0.41) | SOS2CTSKCTSS | |
| SCHEMBL2952857 | 0.71 | IDH1 (0.38) | SOS2CTSKCTSS | |
| SCHEMBL2960932 | 0.71 | CTSK (0.38) | SOS2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424336-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |