Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763346 | 0.82 | LMNA (0.58) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL4658369 | 0.81 | KMT2A (0.55) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL30894837 | 0.81 | KMT2A (0.55) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL6602932 | 0.80 | ALDH1A1 (0.47) | KMT2AOPRK1MEN1ALDH1A1ACHE | |
| SCHEMBL17478740 | 0.79 | KMT2A (0.52) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL30894828 | 0.78 | ALDH1A1 (0.53) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL7686142 | 0.78 | KMT2A (0.59) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL6603601 | 0.78 | KMT2A (0.49) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL5214685 | 0.77 | ALDH1A1 (0.58) | KMT2AOPRK1MEN1APEX1ALDH1A1 | |
| SCHEMBL6204514 | 0.76 | KDM4E (0.50) | KMT2AOPRK1MEN1APEX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |