Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605853 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2AMEN1MAPTOPRK1 | |
| SCHEMBL6599742 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1BRAFTNNI3K | |
| SCHEMBL6605394 | 0.75 | NUDT1 (0.44) | ALDH1A1BRAFTNNI3KMAPTACHE | |
| SCHEMBL4820926 | 0.73 | ABCG2 (0.51) | ALDH1A1KMT2AMEN1MAPTOPRK1 | |
| SCHEMBL4821056 | 0.73 | NPBWR1 (0.51) | ALDH1A1KMT2AMEN1MAPTOPRK1 | |
| SCHEMBL5873652 | 0.71 | KMT2A (0.51) | ALDH1A1KMT2AMEN1MAPTOPRK1 | |
| SCHEMBL9587522 | 0.70 | ABCG2 (0.48) | ALDH1A1KMT2AOPRK1ABCG2ACHE | |
| SCHEMBL8471116 | 0.70 | ACHE (0.47) | ALDH1A1KMT2AMEN1OPRK1L3MBTL1 | |
| SCHEMBL6593674 | 0.70 | KMT2A (0.52) | ALDH1A1KMT2AMEN1MAPTOPRK1 | |
| SCHEMBL2986361 | 0.70 | ACHE (0.47) | ALDH1A1KMT2AMEN1OPRK1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |