Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486254 | 0.83 | RAB9A (0.39) | CNR1RAB9AALDH1A1HPGDTSHR | |
| SCHEMBL9385618 | 0.82 | MAPT (0.36) | CNR1RAB9AALDH1A1TSHRRECQL | |
| SCHEMBL6209005 | 0.77 | MAPT (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL9850905 | 0.75 | ALDH1A1 (0.40) | CNR1ALDH1A1TSHRL3MBTL1HSD11B1 | |
| SCHEMBL5727163 | 0.73 | ALOX5 (0.52) | RAB9AALDH1A1MAPTNPC1PTGDR2 | |
| SCHEMBL5727838 | 0.73 | SMN1; SMN2 (0.56) | CNR1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL27579832 | 0.73 | RAB9A (0.33) | CNR1RAB9ARECQLNPC1L3MBTL1 | |
| SCHEMBL5727580 | 0.70 | KDM4E (0.58) | RAB9AALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL5726852 | 0.69 | KDM4E (0.59) | RAB9AALDH1A1HPGDTSHRRECQL | |
| SCHEMBL5726389 | 0.69 | CDC7 (0.50) | RAB9AALDH1A1HPGDRECQLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922036-B1 | ARYLALKANOYL PYRIDAZINES | MERCK PATENT GMBH (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-0763534-B1 | Arylalkyl-diazinone derivatives as phosphodiesterase IV inhibitors | MERCK PATENT GMBH (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-1143944-A3 | USE OF ARYLALKANOYLPYRIDAZINES | MERCK PATENT GmbH (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-1143944-A2 | USE OF ARYLALKANOYLPYRIDAZINES | MERCK PATENT GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000059484-A2 | USE OF ARYLALKANOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2000-10-12 | — | — | WO | disclosed |
| EP-0922036-A1 | ARYLALKANOYL PYRIDAZINES | MERCK PATENT GmbH (DE) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998006704-A1 | ARYLALKANOYL PYRIDAZINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |
| EP-0763534-A1 | Arylalkyl-diazinone derivatives as phosphodiesterase IV inhibitors | MERCK PATENT GmbH (DE) | 1997-03-19 | — | — | EP | disclosed |
| EP-0199675-A1 | Heterocyclic penem compounds | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |