Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073181 | 0.77 | TERT (0.55) | TERTNCF1POLBCYP1A2KDM4E | |
| SCHEMBL6606041 | 0.76 | NQO2 (0.50) | TERTNR4A2NCF1POLBKDM4E | |
| SCHEMBL13701566 | 0.71 | LMNA (0.58) | TERTCYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL4077093 | 0.69 | TERT (0.86) | TERTMEN1ALOX15KMT2A | |
| SCHEMBL6790532 | 0.69 | CYP1A2 (0.60) | TERTNCF1CYP1A2KDM4ETDP1 | |
| SCHEMBL6600747 | 0.69 | TERT (0.54) | TERTNCF1TSHRMAPK1CYP1A2 | |
| SCHEMBL6614139 | 0.69 | TERT (0.43) | TERTNR4A2NCF1POLBTSHR | |
| SCHEMBL6600579 | 0.69 | POLB (0.64) | TERTNR4A2POLBMAPTKMT2A | |
| SCHEMBL5849336 | 0.69 | TERT (0.64) | TERTMEN1ALOX15KMT2A | |
| SCHEMBL6617731 | 0.67 | TERT (0.51) | TERTNCF1TSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |