Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663549 | 0.93 | PYCR1 (0.43) | MEN1KMT2AHTTMAOBLMNA | |
| Pyridine SCHEMBL2890264 | 0.87 | KMT2A (0.41) | MEN1KMT2AHTTMAOBLMNA | |
| SCHEMBL28260797 | 0.86 | PYCR1 (0.46) | PYCR1USP2CYP3A4ALDH1A1MAPT | |
| SCHEMBL16573868 | 0.77 | RAB9A (0.41) | MEN1KMT2AMAOBMAOAALDH1A1 | |
| SCHEMBL18803298 | 0.75 | AOC3 (0.43) | — | |
| SCHEMBL28672312 | 0.75 | PYCR1 (0.42) | MAOBLMNAMAOAPYCR1TSHR | |
| SCHEMBL4512814 | 0.74 | MEN1 (0.42) | MEN1KMT2AHTTLMNATSHR | |
| SCHEMBL3252000 | 0.74 | MEN1 (0.42) | MEN1KMT2AHTTLMNATSHR | |
| SCHEMBL209159 | 0.74 | KMT2A (0.48) | MEN1KMT2AHTTLMNATSHR | |
| SCHEMBL1344357 | 0.74 | KMT2A (0.42) | MEN1KMT2AHTTMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-B1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | claimed |
| EP-0335676-B1 | Developer for developing electrostatic image and image forming method | CANON KK (JP) | 1996-01-03 | — | — | EP | claimed |
| EP-0131374-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES | PFIZER INC. (US) | 1988-11-23 | — | — | EP | claimed |
| US-8633337-B2 | Method and synthesis | GE HEALTHCARE LIMITED (GB) | 2014-01-21 | — | — | US | disclosed |
| US-20130060064-A1 | METHOD AND SYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2013-03-07 | — | — | US | disclosed |
| EP-0383621-A1 | Diphenyldiacetylene derivative | TODA KOGYO CORP. (JP) | 1990-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060064-A1 | METHOD AND SYNTHESIS | RNMT, GMPS, GDA | MEN1 677/4885KMT2A 1980/4885HTT 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.