Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823858 | 0.77 | ALDH1A1 (0.52) | CA2CA9CA1LMNAALDH1A1 | |
| SCHEMBL3242840 | 0.75 | MEN1 (0.39) | MEN1KMT2AHTTCA12CA2 | |
| SCHEMBL2584786 | 0.75 | ACHE (0.44) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL4512814 | 0.74 | MEN1 (0.42) | MEN1KMT2AHTTCA12CA2 | |
| SCHEMBL6606508 | 0.74 | MEN1 (0.42) | MEN1KMT2AHTTCA12CA2 | |
| SCHEMBL209159 | 0.74 | KMT2A (0.48) | MEN1KMT2AHTTCA12CA2 | |
| SCHEMBL1344357 | 0.74 | KMT2A (0.42) | MEN1KMT2AHTTCA12CA2 | |
| SCHEMBL2858411 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2AHTTCA12CA2 | |
| Isothiocyanate SCHEMBL2891675 | 0.72 | ALDH1A1 (0.48) | MEN1KMT2AHTTCA12CA2 | |
| SCHEMBL31058089 | 0.72 | MEN1 (0.41) | MEN1KMT2AHTTCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101861093-A | The aryloxy alkyl imidazoline that replaces with the haloalkyl of used as pesticides | SYNGENTA PARTICIPATIONS AG | 2010-10-13 | — | — | CN | claimed |
| CN-101835758-A | Halogenated aryloxy alkyl imidazolines as sterilant | SYNGENTA PARTICIPATIONS AG | 2010-09-15 | — | — | CN | claimed |
| CN-101627016-A | Compound (I) | SYNGENTA PARTICIPATIONS AG | 2010-01-13 | — | — | CN | claimed |
| CN-101610675-A | Chemical compounds quinoline derivant and they purposes as agricultural chemicals | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | CN | claimed |
| US-20140031376-A1 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-30 | — | — | US | disclosed |
| US-8618329-B2 | Iminopropene compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-31 | — | — | US | disclosed |
| US-20130150392-A1 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-13 | — | — | US | disclosed |
| US-8410316-B2 | Iminopropene compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20110319437-A1 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| US-8084644-B2 | Agricultural pesticide; Wide variety of compounds, for example phenyl N-phenyl-3-(phenylthio)thioacrylimidate; formula X-CH=CH-C(-Y)=N-Z where X, Y and Z are variable | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| CN-101861093-A | The aryloxy alkyl imidazoline that replaces with the haloalkyl of used as pesticides | SYNGENTA PARTICIPATIONS AG | 2010-10-13 | — | — | CN | disclosed |
| CN-101848640-A | The aryloxy alkyl imidazoline that replaces with the nitro of used as pesticides | SYNGENTA PARTICIPATIONS AG | 2010-09-29 | — | — | CN | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4008228-A | Process for preparing 3-methyl-3-cephem antibiotics | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3979369-A | DIENE POLYMER | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031376-A1 | IMINOPROPENE COMPOUND AND USE THEREOF | IMPA1, INPP5A, CTRL | MEN1 55/4885KMT2A 1674/4885HTT 1657/4885 |
| US-20130150392-A1 | IMINOPROPENE COMPOUND AND USE THEREOF | IMPA1, INPP5A, CTRL | MEN1 55/4885KMT2A 1674/4885HTT 1657/4885 |
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | MEN1 300/4885KMT2A 85/4885HTT 3024/4885 |
| US-20110319437-A1 | IMINOPROPENE COMPOUND AND USE THEREOF | IMPA1, INPP5A, CTRL | MEN1 55/4885KMT2A 1674/4885HTT 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.