SCHEMBL6607079

SCHEMBL6607079

Cc1ccc(S(=O)(=O)Nc2cccc(F)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.71
ESR1 P03372 1/20 0.71
FFAR1 O14842 1/20 0.67
CDK1 P06493 1/20 0.67
CCNB1 P14635 1/20 0.67
CCNA2 P20248 1/20 0.67
CDK2 P24941 1/20 0.67
CDK7 P50613 1/20 0.67
CCNH P51946 1/20 0.67
CCNA1 P78396 1/20 0.67
FFAR4 Q5NUL3 1/20 0.67
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA9 Q16790 1/20 0.65
TCF4 P15884 1/20 0.59
CTNNB1 P35222 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
MEN1 O00255 1/20 0.58
GAA P10253 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14877794 0.88 CA12 (0.76) ALDH1A1FFAR1CDK1CCNB1CCNA2
SCHEMBL23555093 0.87 ESR1 (0.71) ALDH1A1ESR1FFAR1CDK1CCNB1
SCHEMBL2566977 0.85 ALDH1A1 (0.68) ALDH1A1ESR1FFAR4MEN1GAA
SCHEMBL3701951 0.85 CA12 (0.71) ALDH1A1FFAR1CDK1CCNB1CCNA2
SCHEMBL13807498 0.84 PGR (0.68) ALDH1A1CA12CA1CA2CA9
SCHEMBL13875341 0.84 L3MBTL1 (0.67) ALDH1A1ESR1FFAR1CDK1CCNB1
SCHEMBL24125035 0.84 HTR6 (0.73) ALDH1A1ESR1CA1CA2CA9
SCHEMBL23555210 0.83 ALDH1A1 (0.66) ALDH1A1ESR1L3MBTL1MEN1GAA
SCHEMBL9001319 0.82 CA1 (0.67) ALDH1A1FFAR1CDK1CCNB1CCNA2
SCHEMBL23555049 0.81 ALDH1A1 (0.63) ALDH1A1ESR1CA1CA2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) 2015-10-15 US disclosed
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) 2015-10-15 US disclosed
EP-1440059-A1 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS Pfizer Products Inc. (US) 2004-07-28 EP disclosed
WO-2003035622-A1 3-AZABICYCLO (3.1.0) HEXANE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS PFIZER PRODUCTS INC. (US) 2003-05-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS KCNJ2, HCN2, HACL2 ALDH1A1 2299/4885ESR1 1677/4885FFAR1 2758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.