Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177597 | 0.80 | METAP2 (0.41) | RAB9AALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL6609394 | 0.80 | PDGFRB (0.41) | RAB9AALOX5KDM5BSMN1; SMN2PDGFRB | |
| SCHEMBL2215451 | 0.79 | MEN1 (0.44) | MAPK1RAB9AALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6165643 | 0.78 | KMT2A (0.41) | RAB9AALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL15029205 | 0.78 | MAPK1 (0.42) | MAPK1RAB9AALDH1A1ALOX5KDM5B | |
| SCHEMBL4874412 | 0.78 | LMNA (0.40) | MAPK1RAB9AALDH1A1KDM5BSMN1; SMN2 | |
| SCHEMBL14404777 | 0.76 | MAPK1 (0.41) | MAPK1RAB9AALDH1A1ALOX5KDM5B | |
| SCHEMBL8356431 | 0.76 | MAPK1 (0.41) | MAPK1RAB9AALDH1A1ALOX5KDM5B | |
| SCHEMBL2419681 | 0.76 | ALDH1A1 (0.48) | MAPK1RAB9AALDH1A1ALOX5KDM5B | |
| SCHEMBL15823275 | 0.76 | RAD51 (0.43) | MAPK1RAB9AALDH1A1ALOX5KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313661-A1 | KINASE MODULATORS FOR THE TREATMENT OF CANCER | SYNOVO GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| EP-1373217-A1 | 2-MERCAPTO-4,5-DIARYLIMIDAZOLE DERIVATIVES AND THE USE THEREOF AS CYCLOOXYGENASE INHIBITORS | Beiersdorf AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076951-A1 | 2-MERCAPTO-4,5-DIARYLIMIDAZOLE DERIVATIVES AND THE USE THEREOF AS CYCLOOXYGENASE INHIBITORS | BEIERSDORF AG (DE) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313661-A1 | KINASE MODULATORS FOR THE TREATMENT OF CANCER | MAP3K10, MAP3K12, MAP3K20 | MAPK1 160/4885RAB9A 2039/4885ALDH1A1 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.