SCHEMBL2215451

SCHEMBL2215451

Sc1nc(-c2ccccc2)c[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
HPGD P15428 3/20 0.39
ADORA2A P29274 3/20 0.39
ADORA1 P30542 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
PDGFRB P09619 1/20 0.39
MAPK1 P28482 1/20 0.38
IDO1 P14902 1/20 0.38
METAP2 P50579 1/20 0.38
KEAP1 Q14145 1/20 0.38
ASIC3 Q9UHC3 1/20 0.38
CYP1A2 P05177 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL7482727 0.86 ADORA2A (0.36) MEN1KMT2ARAB9AALDH1A1L3MBTL1
SCHEMBL4874412 0.81 LMNA (0.40) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL6608440 0.79 MAPK1 (0.41) MEN1KMT2ARAB9AALDH1A1L3MBTL1
SCHEMBL6609394 0.79 PDGFRB (0.41) MEN1KMT2ARAB9ASMN1; SMN2PDGFRB
SCHEMBL6177597 0.79 METAP2 (0.41) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL27717280 0.79 MAPK1 (0.49) RAB9AALDH1A1PDGFRBMAPK1METAP2
SCHEMBL5004823 0.79 ALDH1A1 (0.50) MEN1KMT2ARAB9AALDH1A1HPGD
Hydrochloric Acid SCHEMBL6165643 0.78 KMT2A (0.41) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL10908283 0.77 KDM4E (0.46) MEN1KMT2ARAB9AALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL27695082 0.77 MAPK1 (0.48) RAB9AALDH1A1PDGFRBMAPK1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3127173-A1 ELECTROACTIVE ACTUATOR AND METHOD FOR ITS PRODUCTION Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2017-02-08 EP claimed
US-9422499-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 US claimed
US-9422498-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 US claimed
US-9422502-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 US claimed
WO-2015153021-A2 LOW VISCOSITY, LOW VOLATILITY LUBRICATING BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-08 WO claimed
WO-2015153022-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-08 WO claimed
WO-2015153023-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-08 WO claimed
US-20150275128-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-01 US claimed
US-20150275117-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-01 US claimed
US-20150275129-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-01 US claimed
US-5910391-A SUBJECTING PLATE TO EXPOSURE, TREATING WITH DEVELOPING SOLUTION, AND WASHING WITH NITROGEN-CONTAINING HETEROCYCLE COMPOUND HAVING MERCAPTO OR THIONE GROUP MITSUBISHI PAPER MILLS LIMITED (JP) 1999-06-08 US claimed
US-5851723-A Process for making lithographic printing plate MITSUBISHI PAPER MILLS LIMITED (JP) 1998-12-22 US claimed
US-5738969-A WATER INSOLUBLE COMPOUND HAVING MERCAPTO OR THIONE GROUP, AND SULFONATED STYRENE-CONTAINING POLYMER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-04-14 US claimed
US-4080493-A POLYBUTADIENE, POLYISOPRENE, GELATION INHIBITOR SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US claimed
US-12384813-B2 Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates MIRECA MEDICINES GMBH (DE) 2025-08-12 US disclosed
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US disclosed
CN-115297829-A Hair dye 株式会社NIL 2022-11-04 CN disclosed
US-4230792-A COMPLEXING SILVER WITH THIOL OR THIONE MITSUBISHI PAPER MILLS, LTD. (JP) 1980-10-28 US disclosed
US-4161571-A GELATION INHIBITORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-07-17 US disclosed
US-4080493-A POLYBUTADIENE, POLYISOPRENE, GELATION INHIBITOR SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PRKAG3 MEN1 2620/4885KMT2A 2118/4885RAB9A 4339/4885
US-12384813-B2 Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates PRKG1, PRKG2, PRKAG3 MEN1 2653/4885KMT2A 2092/4885RAB9A 4342/4885
US-20150275117-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS ATXN10, KCNK10, F12 MEN1 4063/4885KMT2A 3822/4885RAB9A 3980/4885
US-20150275128-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS F12, OR10J3, ATXN10 MEN1 4433/4885KMT2A 3894/4885RAB9A 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.