Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611305 | 0.80 | BCHE (0.59) | BCHEACHESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6609227 | 0.80 | BCHE (0.55) | BCHEACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL6611149 | 0.78 | MGLL (0.57) | BCHEACHESMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5841173 | 0.77 | POLB (0.59) | SMN1; SMN2LMNAHTTALDH1A1KMT2A | |
| SCHEMBL6613573 | 0.77 | POLB (0.49) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6612825 | 0.77 | POLB (0.59) | SMN1; SMN2LMNAHTTALDH1A1KMT2A | |
| SCHEMBL6608839 | 0.76 | BCHE (0.50) | BCHEACHESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1081511 | 0.75 | FABP7 (0.56) | BCHEACHEFABP7FABP5SMN1; SMN2 | |
| SCHEMBL6610605 | 0.75 | ACHE (0.49) | BCHEACHESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6616272 | 0.74 | BCHE (0.47) | BCHEACHELMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | claimed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | claimed |
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |