Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609227 | 0.90 | BCHE (0.55) | MGLLFAAHACHEBCHEALDH1A1 | |
| SCHEMBL6611305 | 0.86 | BCHE (0.59) | ACHEBCHEALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6614762 | 0.84 | MGLL (0.60) | MGLLFAAHPOLBALDH1A1 | |
| SCHEMBL5843865 | 0.82 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6615276 | 0.81 | ACHE (0.45) | ACHEBCHEPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6613964 | 0.81 | CYP1A2 (0.48) | ACHEBCHEALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6608839 | 0.79 | BCHE (0.50) | ACHEBCHEALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6610605 | 0.79 | ACHE (0.49) | ACHEBCHEALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6608925 | 0.78 | BCHE (0.41) | ACHEBCHEPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6614668 | 0.77 | MGLL (0.55) | MGLLFAAHBCHEPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |