Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610259 | 0.91 | ACHE (0.37) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6614116 | 0.87 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAHTTMAPT | |
| SCHEMBL5843041 | 0.87 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6613618 | 0.86 | GFER (0.44) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6615771 | 0.85 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HPGDACHEBCHE | |
| SCHEMBL6611922 | 0.84 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6665519 | 0.82 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6624165 | 0.82 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6613161 | 0.80 | RXFP3 (0.37) | ALDH1A1L3MBTL1LMNAHTTHPGD | |
| SCHEMBL6614053 | 0.80 | ALOX15 (0.41) | ALDH1A1L3MBTL1LMNAHPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |