Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 10/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483160 | 0.96 | CCR5 (0.52) | SIGMAR1CCR5CXCR4CCR3 | |
| SCHEMBL6615585 | 0.96 | CCR5 (0.52) | SIGMAR1CCR5CXCR4CCR3 | |
| SCHEMBL6610245 | 0.95 | CCR3 (0.51) | SIGMAR1CCR5CXCR4CCR3 | |
| SCHEMBL6613893 | 0.92 | OPRM1 (0.48) | SIGMAR1CCR5CXCR4CCR3 | |
| SCHEMBL6608842 | 0.88 | CCR5 (0.53) | SIGMAR1CCR5CXCR4 | |
| SCHEMBL6612763 | 0.87 | CCR5 (0.52) | SIGMAR1CCR5CXCR4CCR3 | |
| SCHEMBL6612028 | 0.87 | LMNA (0.51) | SIGMAR1CCR5 | |
| SCHEMBL6613900 | 0.85 | CCR5 (0.63) | SIGMAR1CCR5CXCR4 | |
| SCHEMBL6611815 | 0.85 | CCR5 (0.63) | SIGMAR1CCR5CXCR4 | |
| SCHEMBL6611611 | 0.84 | CCR5 (0.52) | SIGMAR1CCR5CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |